An official report, addressing concerns about the many implications of genetic testing, outlined policy guidelines and legislative recommendations intended to avoid involuntary and/or ineffective testing, and to protect confidentiality. The report identified urgent concerns, such as quality control measures (including federal oversight for testing laboratories) and better genetics training for medical practitioners. It recommended voluntary screening, urged couples in high-risk populations to consider carrier screening, and advised caution in using and interpreting pre-symptomatic or predictive tests, because certain information could easily be misused or misinterpreted.
About three in every 100 children are born with a severe disorder presumed to be genetic or partially genetic in origin. Genes, often in concert with environmental factors, are being linked to the causes of many common adult diseases such as heart disease, hypertension (high blood pressure), various cancers, Alzheimer’s disease, etc. Tests to determine predisposition to a variety of conditions are under study, and some are beginning to be applied.
The report recommended that all screening, including screening of newborns, be voluntary. Citing the results of two different voluntary newborn screening programs, the report said these programs can achieve compliance rates equal to or better than those of obligatory programs. State health departments could eventually require the offering of tests for diagnosing treatable conditions in newborns, however, careful pilot studies for conditions diagnosable at birth need to be done first.
Although the report asserted that it would prefer that all screening be voluntary, it did note that if a state requires newborn screening for a particular condition, the state should do so only if there is strong evidence that a newborn would benefit from effective treatment at the earliest possible age. Newborn screening is the most common type of genetic screening today. More than four million newborns are tested annually so that effective treatment can be started in a few hundred infants.
Prenatal (preceding birth) testing can pose the most difficult issues. The ability to diagnose genetic disorders in the fetus(胎儿)far exceeds any ability to treat or cure them. Parents must be fully informed about risks and benefits of testing procedures, the nature and variability of the disorders they would disclose, and the options available if test results are positive.
Obtaining informed consent—a process that would include educating participants, not just processing documents—would enhance voluntary participation. When offered testing, parents should receive comprehensive counseling, which should be nondirective. Relevant medical advice, however, is recommended for treatable or preventable conditions.
Genetics also can predict whether certain diseases might develop later in life. For single-gene diseases, population screening should only be considered for treatable or preventable conditions of relatively high frequency. Children should be tested only for disorders for which effective treatments or preventive measures could be applied early in life.
The report aims to______.
A:offer a detailed description of genetic testing process B:stress the need for caution in the use of newborn screening C:interpret the significance of genetic testing to the public D:state the chief points of the policy guidelines on genetic screening
An official report, addressing concerns about the many implications of genetic testing, outlined policy guidelines and legislative recommendations intended to avoid involuntary and/or ineffective testing, and to protect confidentiality. The report identified urgent concerns, such as quality control measures (including federal oversight for testing laboratories) and better genetics training for medical practitioners. It recommended voluntary screening, urged couples in high-risk populations to consider carrier screening, and advised caution in using and interpreting pre-symptomatic or predictive tests, because certain information could easily be misused or misinterpreted.
About three in every 100 children are born with a severe disorder presumed to be genetic or partially genetic in origin. Genes, often in concert with environmental factors, are being linked to the causes of many common adult diseases such as heart disease, hypertension (high blood pressure), various cancers, Alzheimer’s disease, etc. Tests to determine predisposition to a variety of conditions are under study, and some are beginning to be applied.
The report recommended that all screening, including screening of newborns, be voluntary. Citing the results of two different voluntary newborn screening programs, the report said these programs can achieve compliance rates equal to or better than those of obligatory programs. State health departments could eventually require the offering of tests for diagnosing treatable conditions in newborns, however, careful pilot studies for conditions diagnosable at birth need to be done first.
Although the report asserted that it would prefer that all screening be voluntary, it did note that if a state requires newborn screening for a particular condition, the state should do so only if there is strong evidence that a newborn would benefit from effective treatment at the earliest possible age. Newborn screening is the most common type of genetic screening today. More than four million newborns are tested annually so that effective treatment can be started in a few hundred infants.
Prenatal (preceding birth) testing can pose the most difficult issues. The ability to diagnose genetic disorders in the fetus(胎儿)far exceeds any ability to treat or cure them. Parents must be fully informed about risks and benefits of testing procedures, the nature and variability of the disorders they would disclose, and the options available if test results are positive.
Obtaining informed consent—a process that would include educating participants, not just processing documents—would enhance voluntary participation. When offered testing, parents should receive comprehensive counseling, which should be nondirective. Relevant medical advice, however, is recommended for treatable or preventable conditions.
Genetics also can predict whether certain diseases might develop later in life. For single-gene diseases, population screening should only be considered for treatable or preventable conditions of relatively high frequency. Children should be tested only for disorders for which effective treatments or preventive measures could be applied early in life.
One intention of the policy guidelines was to______.
A:preserve privacy in genetic testing B:implement compulsory testing C:minimize concerns about quality control D:endorse the expansion of screening programs
An official report, addressing concerns about the many implications of genetic testing, outlined policy guidelines and legislative recommendations intended to avoid involuntary and/or ineffective testing, and to protect confidentiality. The report identified urgent concerns, such as quality control measures (including federal oversight for testing laboratories) and better genetics training for medical practitioners. It recommended voluntary screening, urged couples in high-risk populations to consider carrier screening, and advised caution in using and interpreting pre-symptomatic or predictive tests, because certain information could easily be misused or misinterpreted.
About three in every 100 children are born with a severe disorder presumed to be genetic or partially genetic in origin. Genes, often in concert with environmental factors, are being linked to the causes of many common adult diseases such as heart disease, hypertension (high blood pressure), various cancers, Alzheimer’s disease, etc. Tests to determine predisposition to a variety of conditions are under study, and some are beginning to be applied.
The report recommended that all screening, including screening of newborns, be voluntary. Citing the results of two different voluntary newborn screening programs, the report said these programs can achieve compliance rates equal to or better than those of obligatory programs. State health departments could eventually require the offering of tests for diagnosing treatable conditions in newborns, however, careful pilot studies for conditions diagnosable at birth need to be done first.
Although the report asserted that it would prefer that all screening be voluntary, it did note that if a state requires newborn screening for a particular condition, the state should do so only if there is strong evidence that a newborn would benefit from effective treatment at the earliest possible age. Newborn screening is the most common type of genetic screening today. More than four million newborns are tested annually so that effective treatment can be started in a few hundred infants.
Prenatal (preceding birth) testing can pose the most difficult issues. The ability to diagnose genetic disorders in the fetus(胎儿)far exceeds any ability to treat or cure them. Parents must be fully informed about risks and benefits of testing procedures, the nature and variability of the disorders they would disclose, and the options available if test results are positive.
Obtaining informed consent—a process that would include educating participants, not just processing documents—would enhance voluntary participation. When offered testing, parents should receive comprehensive counseling, which should be nondirective. Relevant medical advice, however, is recommended for treatable or preventable conditions.
Genetics also can predict whether certain diseases might develop later in life. For single-gene diseases, population screening should only be considered for treatable or preventable conditions of relatively high frequency. Children should be tested only for disorders for which effective treatments or preventive measures could be applied early in life.
A:preserve privacy in genetic testing B:implement compulsory testing C:minimize concerns about quality control D:endorse the expansion of screening programs
It is a wise father that knows his own child, but today a man can boost his paternal (fatherly) wisdom— or at least confirm that he’s the kid’s dad. All he needs to do is shell out $30 for paternity testing kit (PTK) at his local drugstore—and another $120 to get the results.
More than 60,000 people have purchased the PTKs since they first became available without prescriptions last year, according to Doug Fogg, chief operating officer of Identigene, which makes the over-the-counter kits. More than two dozen companies sell DNA tests directly to the public, ranging in price from a few hundred dollars to more than $ 2,500.
Among the most popular: paternity and kinship testing, which adopted children can use to find their biological relatives and families can use to track down kids put up for adoption. DNA testing is also the latest rage among passionate genealogists—and supports businesses that offer to search for a family’s geographic roots.
Most tests require collecting cells by swabbing saliva in the mouth and sending it to the company for testing. All tests require a potential candidate with whom to compare DNA.
But some observers are skeptical. "There is a kind of false precision being hawked by people claiming they are doing ancestry testing," says Troy Duster, a New York University sociologist. He notes that each individual has many ancestors—numbering in the hundreds just a few centuries back. Yet most ancestry testing only considers a single lineage, either the Y chromosome inherited through men in a father’s line or mitochondrial DNA, which is passed down only from mothers. This DNA can reveal genetic information about only one or two ancestors, even though, for example, just three generations back people also have six other great-grandparents or, four generations back, 14 other great-great-grandparents.
Critics also argue that commercial genetic testing is only as good as the reference collections to which a sample is compared. Databases used by some companies don’t rely on data collected systematically but rather lump together information from different research projects. This means that a DNA database may have a lot of data from some regions and not others, so a person’s test results may differ depending on the company that processes the results. In addition, the computer programs a company uses to estimate relationships may be patented and not subject to peer review or outside evaluation.
A:Fors and Againsts of DNA Testing B:DNA Testing and It Problems C:DNA Testing Outside the Lab D:Lies Behind DNA Testing
An official report, addressing concerns about the many implications of genetic testing, outlined policy guidelines and legislative recommendations intended to avoid involuntary and/or ineffective testing, and to protect confidentiality. The report identified urgent concerns, such as quality control measures (including federal oversight for testing laboratories) and better genetics training for medical practitioners. It recommended voluntary screening, urged couples in high-risk populations to consider carrier screening, and advised caution in using and interpreting pre-symptomatic or predictive tests, because certain information could easily be misused or misinterpreted.
About three in every 100 children are born with a severe disorder presumed to be genetic or partially genetic in origin. Genes, often in concert with environmental factors, are being linked to the causes of many common adult diseases such as heart disease, hypertension (high blood pressure), various cancers, Alzheimer’s disease, etc. Tests to determine predisposition to a variety of conditions are under study, and some are beginning to be applied.
The report recommended that all screening, including screening of newborns, be voluntary. Citing the results of two different voluntary newborn screening programs, the report said these programs can achieve compliance rates equal to or better than those of obligatory programs. State health departments could eventually require the offering of tests for diagnosing treatable conditions in newborns, however, careful pilot studies for conditions diagnosable at birth need to be done first.
Although the report asserted that it would prefer that all screening be voluntary, it did note that if a state requires newborn screening for a particular condition, the state should do so only if there is strong evidence that a newborn would benefit from effective treatment at the earliest possible age. Newborn screening is the most common type of genetic screening today. More than four million newborns are tested annually so that effective treatment can be started in a few hundred infants.
Prenatal (preceding birth) testing can pose the most difficult issues. The ability to diagnose genetic disorders in the fetus(胎儿)far exceeds any ability to treat or cure them. Parents must be fully informed about risks and benefits of testing procedures, the nature and variability of the disorders they would disclose, and the options available if test results are positive.
Obtaining informed consent—a process that would include educating participants, not just processing documents—would enhance voluntary participation. When offered testing, parents should receive comprehensive counseling, which should be nondirective. Relevant medical advice, however, is recommended for treatable or preventable conditions.
Genetics also can predict whether certain diseases might develop later in life. For single-gene diseases, population screening should only be considered for treatable or preventable conditions of relatively high frequency. Children should be tested only for disorders for which effective treatments or preventive measures could be applied early in life.
A:offer a detailed description of genetic testing process B:stress the need for caution in the use of newborn screening C:interpret the significance of genetic testing to the public D:state the chief points of the policy guidelines on genetic screening
Text 2
It is a wise father that knows his own
child, but today a man can boost his paternal (fatherly) wisdom— or at least
confirm that he’s the kid’s dad. All he needs to do is shell out $30 for
paternity testing kit (PTK) at his local drugstore—and another $120 to get the
results. More than 60,000 people have purchased the PTKs since they first became available without prescriptions last year, according to Doug Fogg, chief operating officer of Identigene, which makes the over-the-counter kits. More than two dozen companies sell DNA tests directly to the public, ranging in price from a few hundred dollars to more than $ 2,500. Among the most popular: paternity and kinship testing, which adopted children can use to find their biological relatives and families can use to track down kids put up for adoption. DNA testing is also the latest rage among passionate genealogists—and supports businesses that offer to search for a family’s geographic roots. Most tests require collecting cells by swabbing saliva in the mouth and sending it to the company for testing. All tests require a potential candidate with whom to compare DNA. But some observers are skeptical. "There is a kind of false precision being hawked by people claiming they are doing ancestry testing," says Troy Duster, a New York University sociologist. He notes that each individual has many ancestors—numbering in the hundreds just a few centuries back. Yet most ancestry testing only considers a single lineage, either the Y chromosome inherited through men in a father’s line or mitochondrial DNA, which is passed down only from mothers. This DNA can reveal genetic information about only one or two ancestors, even though, for example, just three generations back people also have six other great-grandparents or, four generations back, 14 other great-great-grandparents. Critics also argue that commercial genetic testing is only as good as the reference collections to which a sample is compared. Databases used by some companies don’t rely on data collected systematically but rather lump together information from different research projects. This means that a DNA database may have a lot of data from some regions and not others, so a person’s test results may differ depending on the company that processes the results. In addition, the computer programs a company uses to estimate relationships may be patented and not subject to peer review or outside evaluation. |
A:Fors and Againsts of DNA Testing B:DNA Testing and It Problems C:DNA Testing Outside the Lab D:Lies Behind DNA Testing
第一篇DNA testing DNA testing reveals the genes of each individual person. Since the early twentieth century scientists have known that all human characteristics are contained in a person’s genes and are passed from parents to children. Genes work as a chemical instruction manual for each part and each function of the body. Their basic chemical element is called DNA, a copy of which can be found in every cell. The existence of genes and the chemical structure of DNA were understood by the mid-1900s, but scientists have only recently been able to identify a person from just a drop of blood or a single hair. One of the most important uses of DNA testing is in criminal investigation. The very first use of DNA testing in a criminal case was in 1985 in Great Britain, when a man confessed to killing a young woman in the English countryside. Because police had found samples of the killer’s DNA at the scene of the crime, a biologist suggested that it might be possible to compare that DNA to some from the confessor’s blood. To everyone’s surprise, the tests showed that he was not the killer. Nor was he guilty of a similar murder that had happened some time earlier. At that point he admitted that he had confessed to the crimes out of fear and police pressure. The police then asked 5, 000 local men for samples of their blood, and DNA testing revealed that one of them was the real murderer, so the first man was set free. In 1992, two law professors, Peter Neufeld and Barry Scheck, decided to use DNA evidence to help set free such mistakenly convicted prisoners. With the help of their students, they created a not- for-profit organization called the Innocence Project. Most of their clients are poor men, many from racial and ethnic minorities. In fact, studies have shown that U. S. judges and juries are often influenced by racial and ethnic background, and that people from minority groups are more likely to be convicted. Some of these men had been sentenced to death, a form of punishment used in thirty eight states out of fifty (as of 2006). For most of these prisoners, their only hope was another trial in which DNA testing could be used to prove their innocence. Between 1992 and 2006, the Innocence Project helped free 100 men. Some of these prisoners had been in jail for ten, twenty years or more for crimes they did not commit. However, the goal of the Innocence Project is not simply to set free those who are wrongfully in jail. They also hope to bring about real changes in the criminal justice system. Illinois in the late 1990s, a group of journalism students at Northwestern University were able to bring about such a change in that state. They began investigating some Illinois prisoners who claimed to be innocent. Through DNA testing, the students were able to prove that in fact the prisoners were not guilty of the crimes they had been accused of. Thirteen of these men were set free, and in 2000, Governor Ryan of Illinois decided to stop carrying out death sentences until further study could be made of the prisoners’ cases. The use of DNA in criminal cases is still being debated around the world. Some fear that governments will one day keep records of everyone’s DNA, which could put limits on the privacy and freedom of citizens. Other people mistrust the science of DNA testing and think that lawyers use it to get their clients free whether or not they are guilty. But for those whose innocence has been proven and who are now free men, DNA testing has meant nothing less than a return to life. And with the careful use of DNA testing, no innocent person should ever be convicted again. What is the main idea of this passage?
A:DNA testing has changed the American legal system. B:DNA testing has helped innocent men go free in Illinois. C:DNA testing uses genetics to identify a person. D:DNA testing has played a key role in criminal investigation.
Where box testing of software testing is a test for software structure.Which of the following item should noe be included ing the content of white box? ()
A:boundary value analysis B:statement testing C:branch testing D:path testing
White box testing of software testing is a test for software structure. Which of the following item should not be included in the content of white box ?()
A:boundary value analysis B:statement testing C:branch testing D:path testing
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